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Anti-LIMPII/SR-B2 Antibody (3W731) 是一种 Rabbit 抗体,靶向 LIMPII/SR-B2。Anti-LIMPII/SR-B2 Antibody (3W731) 可用于 ELISA。
Anti-LIMPII/SR-B2 Antibody (3W731) 是一种 Rabbit 抗体,靶向 LIMPII/SR-B2。Anti-LIMPII/SR-B2 Antibody (3W731) 可用于 ELISA。
产品描述 | Anti-LIMPII/SR-B2 Antibody (3W731) is a Rabbit antibody targeting LIMPII/SR-B2. Anti-LIMPII/SR-B2 Antibody (3W731) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3W731 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SCARB2 / LIMP2 (rM SCARB2; TMPY-01434; Met 1-Thr 432; NP_031670.1). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses’ propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, and may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse SCARB2 protein (TMPY-01434) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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