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Anti-P2Y6 Polyclonal Antibody

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货号 TMAB-09863

Anti-P2Y6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 P2Y6。Anti-P2Y6 Polyclonal Antibody 可用于 WB。

Anti-P2Y6 Polyclonal Antibody

Anti-P2Y6 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09863

Anti-P2Y6 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 P2Y6。Anti-P2Y6 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-P2Y6 Polyclonal Antibody is a Rabbit antibody targeting P2Y6. Anti-P2Y6 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Nucleotides are emerging as important extracellular signaling molecules that mediate several effects, such as proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, P2X and P2Y. The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. The P2Y receptors are differentially expressed in several tissue types, such as heart, lung and brain. However, all P2Y receptors are expressed in leukocytes, which suggests a role for the P2Y receptor family in the activation of leukocytes and platelets in response to inflammation or vascular damage.
抗原信息
免疫原
KLH conjugated synthetic peptide: human P2Y6
抗原种属
Human
基因名称
P2RY6
基因ID
蛋白名称
P2Y purinoceptor 6
Uniprot ID
功能
Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
化学信息
分子量Theoretical: 36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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