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Anti-UBASH3A Antibody (9G35)

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产品编号 TMAY-02632

Anti-UBASH3A Antibody (9G35) 是一种 Rabbit 抗体,靶向 UBASH3A。Anti-UBASH3A Antibody (9G35) 可用于 ELISA。

Anti-UBASH3A Antibody (9G35)

Anti-UBASH3A Antibody (9G35)

Rating icon 还可以
产品编号 TMAY-02632

Anti-UBASH3A Antibody (9G35) 是一种 Rabbit 抗体,靶向 UBASH3A。Anti-UBASH3A Antibody (9G35) 可用于 ELISA。

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产品介绍

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产品描述
Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
9G35
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human UBASH3A (rh UBASH3A; TMPY-03439; AAH69511.1; Ala354-Asn623).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景UBASH3A is a member of the T-cell ubiquitin ligand (TULA) family. This family consists of two members. Both of them can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of UBASH3A gene results in multiple transcript variants. It interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. UBASH3A promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. UBASH3A also exhibits negligigle protein tyrosine phosphatase activity at neutral pH. It may act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. It may also inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human UBASH3A Protein (TMPY-03439)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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