Name: IL-18BP Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00491
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 358

6-8日内发货

10 μg

¥ 573

6-8日内发货

20 μg

¥ 938

5日内发货

50 μg

¥ 1,830

5日内发货

100 μg

¥ 3,100

5日内发货

200 μg

¥ 5,620

5日内发货

500 μg

¥ 12,400

5日内发货

生物活性

产品描述	Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.14 kDa and the accession number is A0A2K5UDJ4.
生物活性	Immobilized Human IL-18, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus IL-18BP, His Tag with the EC50 of 3.0ng/ml determined by ELISA.
研究背景	Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	A0A2K5UDJ4
蛋白构建	Thr28-Pro207
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	Interleukin-18-binding protein, IL-18BP, Igifbp
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	21.14 kDa (predicted). Due to glycosylation, the protein migrates to 35-65 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

IL-18BP Protein, Cynomolgus, Recombinant (His)

IL-18BP Protein, Cynomolgus, Recombinant (His)

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