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Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591)

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Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591)
产品编号 TMAY-01521
别名 PIG61, Phospho-EGF Receptor (Y1068), p-EGF Receptor (Y1068), p-EGF Receptor (Tyr1068), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (p-Y1068), EGF Receptor (p-Tyr1068)

Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) 是一种 Rabbit 抗体，靶向 Phospho-EGF Receptor (Tyr1068)。Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) 可用于 WB。

Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591)

Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591)

Rating icon 还可以
Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591)
产品编号 TMAY-01521 别名 PIG61, Phospho-EGF Receptor (Y1068), p-EGF Receptor (Y1068), p-EGF Receptor (Tyr1068), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (p-Y1068), EGF Receptor (p-Tyr1068)

Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) 是一种 Rabbit 抗体，靶向 Phospho-EGF Receptor (Tyr1068)。Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) 可用于 WB。

规格价格库存数量
20 μL
¥ 679
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100 μL
¥ 1,984
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产品介绍

生物活性
产品描述
Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr1068). Anti-Phospho-EGF Receptor (Tyr1068) Antibody (4Z591) can be used in WB.
别名PIG61, Phospho-EGF Receptor (Y1068), p-EGF Receptor (Y1068), p-EGF Receptor (Tyr1068), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (p-Y1068), EGF Receptor (p-Tyr1068)
Ig Type
Rabbit IgG
克隆号
4Z591
交叉反应
Human
验证活性
1. Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with EGF using Phospho-EGF Receptor (Tyr1068) rabbit monoclonal Antibody at 1:2000 dilution (upper), or Anti-EGFR Antibody, Rabbit Polyclonal at 1:2000 dilution (lower).
2. Western blot analysis of extracts from serum-starved Hela, treated with EGF (10 ng/mL, 30 min), using Phospho-EGF Receptor (Tyr1068) Antibody and other brands’ antibodies (company C) at dilution of 1:2000, 1:20000 and 1:200000. (Validation Experiment)
3. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with EGF or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-EGF Receptor (Tyr1068) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment)
4. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with EGF using Phospho-EGF Receptor (Tyr1068) rabbit monoclonal Antibody at 1:5000 dilution. (Validation Experiment)
应用
WB
推荐剂量
WB: 1:1000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around Tyr1068 of Human Phospho-EGF Receptor.
纯化方式Protein A
性状Liquid
缓冲液10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
研究背景As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: residues around Tyr1068 of Human Phospho-EGF Receptor
抗原种属
Human
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

pEGF Receptor (Y1068)pEGF Receptor (Tyr1068)EGF Receptor (pY1068)EGF Receptor (pTyr1068)EGF Receptor (phospho-Y1068)EGF Receptor (phospho-Tyr1068)

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4个月前
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