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Anti-GLO1 Antibody (8T474)
还可以产品编号 TMAY-03250
Anti-GLO1 Antibody (8T474) 是一种 Rabbit 抗体，靶向 GLO1。Anti-GLO1 Antibody (8T474) 可用于 ELISA。
Anti-GLO1 Antibody (8T474)
Anti-GLO1 Antibody (8T474)
还可以产品编号 TMAY-03250
Anti-GLO1 Antibody (8T474) 是一种 Rabbit 抗体，靶向 GLO1。Anti-GLO1 Antibody (8T474) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-GLO1 Antibody (8T474) is a Rabbit antibody targeting GLO1. Anti-GLO1 Antibody (8T474) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8T474 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse GLO1 / Glyoxalase 1 (rM GLO1 / Glyoxalase 1; TMPY-01618; NP_079650.3; Ala 2-Ile 184). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of methylglyoxal, a cytotoxic byproduct of glycolysis. Accumulative evidence suggests an important role of GLO1 expression in protection against methylglyoxal-dependent protein adduction and cellular damage associated with diabetes, cancer, and chronological aging. GLO1 / Glyoxalase I has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. GLO1 / Glyoxalase I catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. GLO1 / Glyoxalase I exists in three separable isoforms which originate from two alleles in the genome. These correspond to two homodimers and one heterodimer composed of two subunits showing different electrophoretic properties. GLO1 upregulation may play a functional role in glycolytic adaptations of cancer cells. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse GLO1 / Glyoxalase 1 protein (TMPY-01618) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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