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PTX3 Protein, Mouse, Recombinant (His)
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货号 TMPJ-00981
别名 α-induced protein 5, pentraxin-related protei, pentraxin-related gene, rapidly induced by IL-1 β, pentraxin-related gene, rapidly induced by IL-1 beta, pentraxin-3, pentraxin 3, long, Pentraxin 3, Pentaxin-related protein PTX3, pentaxin-related gene, rapidly induced by IL-1 β, tumor necrosis factor, pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It's subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.
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PTX3 Protein, Mouse, Recombinant (His)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPJ-00981 别名 α-induced protein 5, pentraxin-related protei, pentraxin-related gene, rapidly induced by IL-1 β, pentraxin-related gene, rapidly induced by IL-1 beta, pentraxin-3, pentraxin 3, long, Pentraxin 3, Pentaxin-related protein PTX3, pentaxin-related gene, rapidly induced by IL-1 β, tumor necrosis factor, pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It's subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 693 | 6-8日内发货 | |
| 10 μg | ¥ 1,170 | 6-8日内发货 | |
| 20 μg | ¥ 1,860 | 5日内发货 | |
| 50 μg | ¥ 3,470 | 5日内发货 | |
| 100 μg | ¥ 4,930 | 5日内发货 | |
| 200 μg | ¥ 7,350 | 5日内发货 | |
| 500 μg | ¥ 12,100 | 5日内发货 | |
| 1 mg | ¥ 18,900 | 5日内发货 |
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浓度: 0.5 mg/mL
纯度: Greater than 90% as determined by reducing SDS-PAGE.
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产品介绍
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| 产品描述 | Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It's subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator of immune response. PTX3 may also function in the regulation of the uptake and clearance of apoptotic cells by dendritic cells. An in vivo study showed that PTX3 transgenic mice are more resistant to sepsis and endotoxemia compared to wild-type during inflammatory injury. |
| 种属 | Mouse |
| 表达系统 | HEK293 Cells |
| 标签 | N-6xHis |
| 蛋白编号 | P48759 |
| 氨基酸序列 | Glu18-Ser381 |
| 蛋白构建 | Glu18-Ser381 |
| 蛋白纯度 | Greater than 90% as determined by reducing SDS-PAGE. (QC verified) |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. |
| 别名 | α-induced protein 5, pentraxin-related protei, pentraxin-related gene, rapidly induced by IL-1 β, pentraxin-related gene, rapidly induced by IL-1 beta, pentraxin-3, pentraxin 3, long, Pentraxin 3, Pentaxin-related protein PTX3, pentaxin-related gene, rapidly induced by IL-1 β, tumor necrosis factor, pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5 |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 54 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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