Sphingosine Kinase 1/SPHK1 Protein, Human, Recombinant

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产品编号 TMPY-04432

Sphingosine Kinase 1/SPHK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.7 kDa and the accession number is Q9NYA1-1.

Sphingosine Kinase 1/SPHK1 Protein, Human, Recombinant

一键复制产品信息

产品编号 TMPY-04432

Sphingosine Kinase 1/SPHK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.7 kDa and the accession number is Q9NYA1-1.

规格	价格	库存
5 μg	¥ 582	6-8日内发货
10 μg	¥ 939	6-8日内发货
20 μg	¥ 1,590	5日内发货
50 μg	¥ 3,670	5日内发货

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产品信息

生物活性	The specific activity was determined to be ＞500nmol/min/mg using Sphingosine Kinase Substrate as substrate.
产品描述	Sphingosine Kinase 1/SPHK1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.7 kDa and the accession number is Q9NYA1-1.
种属	Human
表达系统	Baculovirus Insect Cells
标签	Tag Free
蛋白编号	Q9NYA1-1
别名	SPK,SPHK1,SPHK,sphingosine kinase 1
蛋白构建	A DNA sequence encoding the human SPHK1 (Q9NYA1-1)(Met1-Leu384) was fused with two additional amino acids (Gly & Pro) at the N-terminus. Predicted N terminal: Gly
蛋白纯度	> 85 % as determined by SDS-PAGE
分子量	42.7 kDa (predicted); 46 kDa (reducing conditions)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Solution
缓冲液	Supplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.
研究背景	SPHK1, also known as sphingosine Kinase 1, catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes.