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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PKM2 Antibody (5U320)

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货号 TMAB-11500

Anti-PKM2 Antibody (5U320) 是一种 Rabbit 抗体，靶向 PKM2。Anti-PKM2 Antibody (5U320) 可用于 FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB。

Anti-PKM2 Antibody (5U320)

Anti-PKM2 Antibody (5U320)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11500

Anti-PKM2 Antibody (5U320) 是一种 Rabbit 抗体，靶向 PKM2。Anti-PKM2 Antibody (5U320) 可用于 FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-PKM2 Antibody (5U320) is a Rabbit antibody targeting PKM2. Anti-PKM2 Antibody (5U320) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
克隆号
5U320
反应种属
Human,Mouse,Rat
应用FCMICC/IFIFIHC-FrIHC-PWB
推荐剂量
FCM=1:50-100; ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:1000-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Translocates to the nucleus in response to different apoptotic stimuli. Nuclear translocation is sufficient to induce cell death that is caspase independent, isoform-specific and independent of its enzymatic activity.
组织特异性Specifically expressed in proliferating cells, such as embryonic stem cells, embryonic carcinoma cells, as well as cancer cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Catalyzes the final rate-limiting step of glycolysis by mediating the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production.
抗原信息
免疫原
A synthesized peptide: human PKM
抗原种属
Human
基因名称
PKM
基因ID
5315
蛋白名称
Pyruvate kinase PKM
Uniprot ID
P14618
功能
Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
化学信息
分子量Theoretical: 58 kDa. Actual: 58 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
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