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Anti-LRRC33 Polyclonal Antibody

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货号 TMAB-08414

Anti-LRRC33 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRRC33。Anti-LRRC33 Polyclonal Antibody 可用于 WB。

Anti-LRRC33 Polyclonal Antibody

Anti-LRRC33 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08414

Anti-LRRC33 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRRC33。Anti-LRRC33 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-LRRC33 Polyclonal Antibody is a Rabbit antibody targeting LRRC33. Anti-LRRC33 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single pass type I membrane protein.
组织特异性Ubiquitous, with high level of expression found in bone marrow, thymus, liver, lung, intestine and spleen.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景LRRC33 is a 692 amino acid protein that contains 17 LRR repeats. The gene encoding LRRC33 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
抗原信息
免疫原
Recombinant Protein: mouse LRRC33 protein
抗原种属
Mouse
基因名称
NRROS
基因ID
蛋白名称
Transforming growth factor beta activator LRRC33
Uniprot ID
功能
Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex.
May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production.
化学信息
分子量Theoretical: 74 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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