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Anti-LRRC33 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRRC33。Anti-LRRC33 Polyclonal Antibody 可用于 WB。
Anti-LRRC33 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRRC33。Anti-LRRC33 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-LRRC33 Polyclonal Antibody is a Rabbit antibody targeting LRRC33. Anti-LRRC33 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single pass type I membrane protein. |
| 组织特异性 | Ubiquitous, with high level of expression found in bone marrow, thymus, liver, lung, intestine and spleen. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | LRRC33 is a 692 amino acid protein that contains 17 LRR repeats. The gene encoding LRRC33 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3. |
| 免疫原 | Recombinant Protein: mouse LRRC33 protein |
| 抗原种属 | Mouse |
| 基因名称 | NRROS |
| 基因ID | |
| 蛋白名称 | Transforming growth factor beta activator LRRC33 |
| Uniprot ID | |
| 功能 | Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex.
May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production. |
| 分子量 | Theoretical: 74 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |