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Anti-SP1 Antibody (1E912)

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货号 TMAB-13072

Anti-SP1 Antibody (1E912) 是一种 Rabbit 抗体,靶向 SP1。Anti-SP1 Antibody (1E912) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-SP1 Antibody (1E912)

Anti-SP1 Antibody (1E912)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13072

Anti-SP1 Antibody (1E912) 是一种 Rabbit 抗体,靶向 SP1。Anti-SP1 Antibody (1E912) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-SP1 Antibody (1E912) is a Rabbit antibody targeting SP1. Anti-SP1 Antibody (1E912) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
1E912
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location.
组织特异性Up-regulated in adenocarcinomas of the stomach (at protein level).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses.
抗原信息
免疫原
A synthesized peptide: human SP1
抗原种属
Human
基因名称
SP1
基因ID
蛋白名称
Transcription factor Sp1
Uniprot ID
功能
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.
化学信息
分子量Theoretical: 81 kDa. Actual: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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