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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ULK3 Antibody (8N642)

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货号 TMAB-13990

Anti-ULK3 Antibody (8N642) 是一种 Rabbit 抗体，靶向 ULK3。Anti-ULK3 Antibody (8N642) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-ULK3 Antibody (8N642)

Anti-ULK3 Antibody (8N642)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13990

Anti-ULK3 Antibody (8N642) 是一种 Rabbit 抗体，靶向 ULK3。Anti-ULK3 Antibody (8N642) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-ULK3 Antibody (8N642) is a Rabbit antibody targeting ULK3. Anti-ULK3 Antibody (8N642) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
8N642
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Widely expressed. Highest levels observed in fetal brain. In adult tissues, high levels in brain, liver and kidney, moderate levels in testis and adrenal gland and low levels in heart, lung, stomach, thymus, prostate and placenta. In the brain, highest expression in the hippocampus, high levels also detected in the cerebellum, olfactory bulb and optice nerve. In the central nervous system, lowest levels in the spinal cord.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation.
抗原信息
免疫原
A synthesized peptide: human ULK3
抗原种属
Human
基因名称
ULK3
基因ID
25989
蛋白名称
unc-51 like kinase 3
Uniprot ID
Q6PHR2
功能
Serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. May exert this function by promoting GLI1 nuclear localization. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.
化学信息
分子量Theoretical: 53 kDa. Actual: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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