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Anti-SIAE Antibody (6X555)
还可以产品编号 TMAY-02558
Anti-SIAE Antibody (6X555) 是一种 Mouse 抗体，靶向 SIAE。Anti-SIAE Antibody (6X555) 可用于 IHC-P。
Anti-SIAE Antibody (6X555)
Anti-SIAE Antibody (6X555)
还可以产品编号 TMAY-02558
Anti-SIAE Antibody (6X555) 是一种 Mouse 抗体，靶向 SIAE。Anti-SIAE Antibody (6X555) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SIAE Antibody (6X555) is a Mouse antibody targeting SIAE. Anti-SIAE Antibody (6X555) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6X555 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human SIAE in human prostate with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human SIAE in human colon carcinoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SIAE/sialate O-acetylesterase (rh SIAE/sialate O-acetylesterase; TMPY-02952; Q9HAT2-1; Met1-Lys523). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human SIAE/sialate O-acetylesterase Protein (TMPY-02952) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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