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Anti-KAT8 Antibody (7Z632)
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产品编号 TMAC-02298
别名 YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, MYST1, MOZ, MOF, Lysine acetyltransferase 8, KAT 8, hMOF, Histone acetyltransferase KAT8, EC 2.3.1.48
Anti-KAT8 Antibody (7Z632) 是一种 Rabbit 抗体，靶向 KAT8。Anti-KAT8 Antibody (7Z632) 可用于 WB,ICC,IF,IHC,IP,FCM。
Anti-KAT8 Antibody (7Z632)
Anti-KAT8 Antibody (7Z632)
还可以产品编号 TMAC-02298 别名 YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, MYST1, MOZ, MOF, Lysine acetyltransferase 8, KAT 8, hMOF, Histone acetyltransferase KAT8, EC 2.3.1.48
Anti-KAT8 Antibody (7Z632) 是一种 Rabbit 抗体，靶向 KAT8。Anti-KAT8 Antibody (7Z632) 可用于 WB,ICC,IF,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-KAT8 Antibody (7Z632) is a Rabbit antibody targeting KAT8. Anti-KAT8 Antibody (7Z632) can be used in WB,ICC,IF,IHC,IP,FCM. |
| 别名 | YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, MYST1, MOZ, MOF, Lysine acetyltransferase 8, KAT 8, hMOF, Histone acetyltransferase KAT8, EC 2.3.1.48 |
| Ig Type | IgG |
| 克隆号 | 7Z632 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human cervix tissue using anti-KAT8 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human cervix cancer tissue using anti-KAT8 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded rat cervix tissue using anti-KAT8 antibody. Counter stained with hematoxylin. 4. ICC staining KAT8 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining KAT8 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining KAT8 in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. Flow cytometric analysis of K562 cells with KAT8 antibody at 1/100 dilution (yellow) compared with an unlabelled control (cells without incubation with primary antibody; purple).Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | IHC: 1:50-1:200; ICC: 1:50-1:200; FCM: 1:50-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Dosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: within N-terminal human KAT8 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 52 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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