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顶部生物活性储存和溶解信息计算器

Anti-NME1 Antibody (5X305)

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产品编号 TMAY-01938

别名 NME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD

Anti-NME1 Antibody (5X305) 是一种 Rabbit 抗体，靶向 NME1。Anti-NME1 Antibody (5X305) 可用于 IHC-P。

Anti-NME1 Antibody (5X305)

Anti-NME1 Antibody (5X305)

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Rating icon 还可以
产品编号 TMAY-01938 别名 NME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD

Anti-NME1 Antibody (5X305) 是一种 Rabbit 抗体，靶向 NME1。Anti-NME1 Antibody (5X305) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-NME1 Antibody (5X305) is a Rabbit antibody targeting NME1. Anti-NME1 Antibody (5X305) can be used in IHC-P.
别名NME/NM23 nucleoside diphosphate kinase 1, NM23-H1, NM23, NDPK-A, NDPKA, NDKA, NBS, NB, GAAD, AWD
Ig Type
Rabbit IgG
克隆号
5X305
交叉反应
Human
特异性
Human NME1
验证活性
1. Immunochemical staining of human NME1 in human lung cancer with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human NME1 in human hepatoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human NME1 / NDKA (rh NME1 / NDKA; TMPY-04467; NP_000260.1; Ala2-Glu152).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as CKI and Aurora-A/STK15. The second group of proteins acts as downstream effectors for the regulation of specific gene transcriptions, GTP-binding protein functions, and signal transduction in the Erk signal cascade. The third group of proteins can be classified as bi-directionally influencing binding partners of NM23-H1. As a result, the interactions with NM23-H1 and binding partners have implications in the biochemical characterization involved in metastasis and tumorigenesis. NDKA is increased in human postmortem cerebrospinal fluid (CSF), a model of global brain insult, suggesting that measurement in CSF and, more importantly, in plasma may be useful as a biomarker of stroke. Additionally, NM23-H1 significantly reduces metastasis without effects on primary tumor size and was the first discovered metastasis suppressor gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human NME1 / NDKA protein (TMPY-04467)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

NM-23NM 23

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