Tetrahexyldecyl ascorbate (BV-OSC) is a lipophilic precursor of ascorbic acid, a more stable and permeable form of vitamin C. It is a potent anti-photo-aging and anti-hyperpigmentation antioxidant that inhibits MMP enzyme activity.

Tetrahexyldecyl ascorbate单独或与AZ联合作用于人角质形成细胞（HaCaT）和皮肤成纤维细胞（nHDF、aHDF），经0.5-3h孵育后，采用CCK-8、ELISA及基因芯片技术检测发现：Tetrahexyldecyl ascorbate在氧化应激下会降低细胞存活率，而与AZ联用可显著提升细胞活性，联合用药能上调磷脂稳态和角质形成细胞分化相关基因，抑制MMP1、MMP7表达，并促进皮肤成纤维细胞合成胶原蛋白[1]。