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Anti-MTLC Polyclonal Antibody

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Anti-MTLC Polyclonal Antibody
产品编号 TMAB-01175

Anti-MTLC Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MTLC。Anti-MTLC Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-MTLC Polyclonal Antibody

Anti-MTLC Polyclonal Antibody

Rating icon 还可以
Anti-MTLC Polyclonal Antibody
产品编号 TMAB-01175

Anti-MTLC Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MTLC。Anti-MTLC Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-MTLC Polyclonal Antibody is a Rabbit antibody targeting MTLC. Anti-MTLC Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Human,Mouse (predicted:Rat,Dog)
验证活性
1. Sample: Brain (Mouse) Lysate at 40 μg
Primary: Anti-MTLC (TMAB-01175) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/10000 dilution
Predicted band size: 27 kDa
Observed band size: 31 kDa
2. Tissue/cell: human colon carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-MTLC Polyclonal Antibody, Unconjugated (TMAB-01175) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
应用
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Note=Expressed in nuclei of hepatocellular carcinoma cell line Bel7402 cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景MTLC is a 235 amino acid nuclear protein that is thought to regulate certain myc target genes. Downregulated in gastric cancer tissues, MTLC is expressed in the hepatocellular carcinoma cell line, Bel7402. Overexpression of MTLC is thought to influence tumorigenic conversion, promotion of apoptosis genomic instability and inhibition of hematopoietic differentiation. The gene encoding MTLC maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MTLC
抗原种属
Human
基因ID
Uniprot ID
研究领域
Transcription Factors
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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