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Anti-ECM1 Antibody (7C642) 是一种 Mouse 抗体,靶向 ECM1。Anti-ECM1 Antibody (7C642) 可用于 ELISA(Cap)。
Anti-ECM1 Antibody (7C642) 是一种 Mouse 抗体,靶向 ECM1。Anti-ECM1 Antibody (7C642) 可用于 ELISA(Cap)。
产品描述 | Anti-ECM1 Antibody (7C642) is a Mouse antibody targeting ECM1. Anti-ECM1 Antibody (7C642) can be used in ELISA(Cap). |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 7C642 |
交叉反应 | Human |
应用 | ELISA(Cap) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ECM1 (rh ECM1 ; TMPY-07013; NP_004416.1; Met1-Glu540). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ECM1 Protein (TMPY-07013) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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