购物车
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部相关产品产品介绍化学信息储存和溶解信息计算器

Methazolamide-D6

货号 T70186Cas号 1795142-30-1 一键复制产品信息
Rating icon 还可以

Methazolamide-D6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide (T0106) is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide (T0106)reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS)in a primary cortical neuron (PCN)cellular model of subarachnoid hemorrhage (SAH)and reduces cerebral edema in a mouse model of SAH.3 Methazolamide (T0106) is larvicidal,with a 50% larvicidal concentration (LC50)value of 724 ppm,but has no activity when administered in the diet to adult A. aegypti. Formulations containing methazolamide have been used in the treatment of glaucoma.

Methazolamide-D6

一键复制产品信息
Rating icon 还可以
货号 T70186Cas号 1795142-30-1

Methazolamide-D6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide (T0106) is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide (T0106)reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS)in a primary cortical neuron (PCN)cellular model of subarachnoid hemorrhage (SAH)and reduces cerebral edema in a mouse model of SAH.3 Methazolamide (T0106) is larvicidal,with a 50% larvicidal concentration (LC50)value of 724 ppm,but has no activity when administered in the diet to adult A. aegypti. Formulations containing methazolamide have been used in the treatment of glaucoma.

Methazolamide-D6
其他形式的 “Methazolamide-D6”:
MethazolamideT0106554-57-4
现货
规格价格库存数量
1 mg
¥ 5,880
35日内发货
5 mg
¥ 25,500
35日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂
常见问题解答
查看更多
资源下载:产品操作手册

产品介绍

生物活性
产品描述
Methazolamide-D6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide (T0106) is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide (T0106) reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH.3 Methazolamide (T0106) is larvicidal, with a 50% larvicidal concentration (LC50) value of 724 ppm, but has no activity when administered in the diet to adult A. aegypti. Formulations containing methazolamide have been used in the treatment of glaucoma.
化学信息
分子量242.31
分子式C5H2D6N4O3S2
CAS No.1795142-30-1
SmilesN(C(C([2H])([2H])[2H])=O)=C1SC(S(N)(=O)=O)=NN1C([2H])([2H])[2H]
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

NPC18915NPC 18915Methazolamide-d6554-57-4
Related Tags: buy Methazolamide-D6 | purchase Methazolamide-D6 | Methazolamide-D6 cost | order Methazolamide-D6 | Methazolamide-D6 chemical structure | Methazolamide-D6 formula | Methazolamide-D6 molecular weight