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Anti-GAMT Polyclonal Antibody

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货号 TMAB-06327

Anti-GAMT Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GAMT。Anti-GAMT Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-GAMT Polyclonal Antibody

Anti-GAMT Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06327

Anti-GAMT Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GAMT。Anti-GAMT Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-GAMT Polyclonal Antibody is a Rabbit antibody targeting GAMT. Anti-GAMT Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig)
应用IHC-PIHC-FrICC/IFIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Expressed in liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景In the creatine biosynthesis pathway, glycine is converted to guanidinoacetate by amidinotransferase, and guanidinoacetate is then converted to creatine by Guanidinoacetate N-methyltransferase (GAMT). GAMT, a methyltransferase, uses S-adenosylmethionine as the methyl donor for this reaction. Methyltransferases are a type of transferase enzyme which transfers a methyl group to nucleic bases in DNA or amino acids in protein. Encoding a 236 amino acid protein, the human GAMT gene maps to chromosome 19p13.3. Defects in the GAMT gene leads to GAMT deficiency, which is associated with guanidinoacetate accumulation and decreased levels of creatine excretion in brain. Such biochemical changes are thought to lead to various neurological syndromes and muscular hypotonia.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GAMT
抗原种属
Human
基因名称
GAMT
基因ID
蛋白名称
Guanidinoacetate N-methyltransferase
Uniprot ID
化学信息
分子量Theoretical: 26 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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