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Anti-GAMT Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GAMT。Anti-GAMT Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
Anti-GAMT Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GAMT。Anti-GAMT Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-GAMT Polyclonal Antibody is a Rabbit antibody targeting GAMT. Anti-GAMT Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Dog,Pig) |
| 应用 | IHC-PIHC-FrICC/IFIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 组织特异性 | Expressed in liver. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | In the creatine biosynthesis pathway, glycine is converted to guanidinoacetate by amidinotransferase, and guanidinoacetate is then converted to creatine by Guanidinoacetate N-methyltransferase (GAMT). GAMT, a methyltransferase, uses S-adenosylmethionine as the methyl donor for this reaction. Methyltransferases are a type of transferase enzyme which transfers a methyl group to nucleic bases in DNA or amino acids in protein. Encoding a 236 amino acid protein, the human GAMT gene maps to chromosome 19p13.3. Defects in the GAMT gene leads to GAMT deficiency, which is associated with guanidinoacetate accumulation and decreased levels of creatine excretion in brain. Such biochemical changes are thought to lead to various neurological syndromes and muscular hypotonia. |
| 免疫原 | KLH conjugated synthetic peptide: human GAMT |
| 抗原种属 | Human |
| 基因名称 | GAMT |
| 基因ID | |
| 蛋白名称 | Guanidinoacetate N-methyltransferase |
| Uniprot ID |
| 分子量 | Theoretical: 26 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |