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Anti-DKK1 Antibody (4W115)
还可以产品编号 TMAY-00396
Anti-DKK1 Antibody (4W115) 是一种 Mouse 抗体，靶向 DKK1。Anti-DKK1 Antibody (4W115) 可用于 ELISA(Cap)。
Anti-DKK1 Antibody (4W115)
Anti-DKK1 Antibody (4W115)
还可以产品编号 TMAY-00396
Anti-DKK1 Antibody (4W115) 是一种 Mouse 抗体，靶向 DKK1。Anti-DKK1 Antibody (4W115) 可用于 ELISA(Cap)。
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抗原信息
| 产品描述 | Anti-DKK1 Antibody (4W115) is a Mouse antibody targeting DKK1. Anti-DKK1 Antibody (4W115) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4W115 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DKK1 / Dkk-1 (rh DKK1 / Dkk-1; TMPY-00775; NP_036374.1; Met2-His266). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human DKK1 / Dkk-1 Protein (TMPY-00775) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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