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顶部产品介绍抗原信息储存和溶解信息计算器

Anti-SNX17 Polyclonal Antibody

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货号 TMAB-13010

Anti-SNX17 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SNX17。Anti-SNX17 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-SNX17 Polyclonal Antibody

Anti-SNX17 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13010

Anti-SNX17 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SNX17。Anti-SNX17 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍

生物活性
产品描述
Anti-SNX17 Polyclonal Antibody is a Rabbit antibody targeting SNX17. Anti-SNX17 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm
组织特异性Expressed in granulocyte and 198 other tissues
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300.
浓度1mg/ml
研究背景This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]
抗原信息
免疫原
KLH conjugated synthetic peptide: human SNX17
抗原种属
Human
基因名称
SNX17
基因ID
9784
蛋白名称
Sorting nexin-17
功能
Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels (PubMed:15121882, PubMed:15769472).Binds to NPxY sequences in the cytoplasmic tails of target cargos (PubMed:21512128).Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits (PubMed:28892079, PubMed:22492727).Also required for maintenance of normal cell surface levels of APP and LRP1 (PubMed:16712798, PubMed:19005208).Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (PubMed:16712798).7 Publications
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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