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Anti-BHLHE41 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 BHLHE41。Anti-BHLHE41 Polyclonal Antibody 可用于 WB。
Anti-BHLHE41 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 BHLHE41。Anti-BHLHE41 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-BHLHE41 Polyclonal Antibody is a Rabbit antibody targeting BHLHE41. Anti-BHLHE41 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Rat (predicted:Human,Mouse,Dog,Pig,Cow) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highly expressed in skeletal muscle and brain, moderately expressed in pancreas and heart, weakly expressed in placenta, lung, liver and kidney. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | DEC1 is a 412 amino acid, basic helix-loop-helix (bHLH) containing protein that is involved in the control of proliferation and/or differentiation of several cell types including nerve cells, fibroblasts and chondrocytes. The bHLH region of DEC1 is structurally similar to the bHLH regions of the mammalian HES family, Drosophila hairy and Drosophila Enhancer of split m7. DEC1 is a novel direct target for cAMP in a wide range of cells, and is involved in the control of gene expression in cAMP-activated cells. DEC2, also known as SHARP1, is highly expressed in skeletal muscle and brain. The gene encoding human DEC2 maps to chromosome 12p11.23-p12.1. DEC1 and DEC2 play a role in regulating the mammalian molecular clock by suppressing the transcription of specific clock genes. Both DEC1 and DEC2 are detected in the suprachiasmimc nucleus in a circadian fashion. Brief light impulses induce the expression of DEC1 in a phase-dependent manner. |
| 免疫原 | KLH conjugated synthetic peptide: human SHARP1/DEC2 |
| 抗原种属 | Human |
| 基因名称 | BHLHE41 |
| 基因ID | |
| 蛋白名称 | Class E basic helix-loop-helix protein 41 |
| Uniprot ID | |
| 功能 | May be a transcriptional repressor that represses both basal and activated transcription. |
| 分子量 | Theoretical: 50 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |