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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Kir4.1 Polyclonal Antibody

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货号 TMAB-08076

Anti-Kir4.1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Kir4.1。Anti-Kir4.1 Polyclonal Antibody 可用于 WB。

Anti-Kir4.1 Polyclonal Antibody

Anti-Kir4.1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08076

Anti-Kir4.1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Kir4.1。Anti-Kir4.1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Kir4.1 Polyclonal Antibody is a Rabbit antibody targeting Kir4.1. Anti-Kir4.1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Down’s syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Kir4.1
抗原种属
Human
基因名称
KCNJ10
基因ID
3766
蛋白名称
ATP-sensitive inward rectifier potassium channel 10
Uniprot ID
P78508
功能
May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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