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Anti-DKK1 Antibody (4K388)
还可以产品编号 TMAH-00348
别名 SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Anti-DKK1 Antibody (4K388) 是一种抗体，靶向 DKK1。Anti-DKK1 Antibody (4K388) 可用于 ELISA, WB。
Anti-DKK1 Antibody (4K388)
Anti-DKK1 Antibody (4K388)
还可以产品编号 TMAH-00348 别名 SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1
Anti-DKK1 Antibody (4K388) 是一种抗体，靶向 DKK1。Anti-DKK1 Antibody (4K388) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-DKK1 Antibody (4K388) is an antibody targeting DKK1. Anti-DKK1 Antibody (4K388) can be used in ELISA, WB. |
| 别名 | SK, hDkk-1, hDkk1, Dkk-1, Dkk1, Dickkopf-related 1, Dickkopf-1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 4K388 |
| 交叉反应 | Human |
| 验证活性 | Western Blot -Positive WB detected in: 293 whole cell lysate -All lanes: DKK1 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 29 kDa -Observed band size: 38 kDa |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:500-1:5000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human DKK1 |
| 抗原种属 | Human |
| 基因ID | 22943 |
| Uniprot ID | |
| 研究领域 | Cardiovascular, Developmental biology, Immunology, Stem cells |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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