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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CDKN1A Monoclonal Antibody (8N887)

Synonyms: WAF1, SDI1, p21CIP1, P21, MDA-6, CIP1, CDKN1, CAP20
货号 TMAT-0481 一键复制产品信息
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Anti-CDKN1A Monoclonal Antibody (8N887) 是一种 Mouse 抗体，靶向 CDKN1A。Anti-CDKN1A Monoclonal Antibody (8N887) 可用于 IHC,FCM。

Anti-CDKN1A Monoclonal Antibody (8N887)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0481

别名 WAF1, SDI1, p21CIP1, P21, MDA-6, CIP1, CDKN1, CAP20

Anti-CDKN1A Monoclonal Antibody (8N887) 是一种 Mouse 抗体，靶向 CDKN1A。Anti-CDKN1A Monoclonal Antibody (8N887) 可用于 IHC,FCM。

Anti-CDKN1A Monoclonal Antibody (8N887)
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产品介绍

生物活性
产品描述
Anti-CDKN1A Monoclonal Antibody (8N887) is a Mouse antibody targeting CDKN1A. Anti-CDKN1A Monoclonal Antibody (8N887) can be used in IHC,FCM.
别名
WAF1, SDI1, p21CIP1, P21, MDA-6, CIP1, CDKN1, CAP20
Ig Type
IgG1
克隆号
8N887
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CDKN1A (AA: 1-164) expressed in E. Coli.
抗原种属
Human
基因名称
CDKN1A
基因ID
1026
蛋白名称
Cyclin-dependent kinase inhibitor 1
Uniprot ID
P38936
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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