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MICA Protein, Human, Recombinant (His & Avi), Biotinylated

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货号 TMPK-00219

别名 PERB11.1, MICA, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2

TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.

MICA Protein, Human, Recombinant (His & Avi), Biotinylated

MICA Protein, Human, Recombinant (His & Avi), Biotinylated

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00219 别名 PERB11.1, MICA, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2

TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.

规格价格库存数量
5 μg
¥ 568
6-8日内发货
10 μg
¥ 928
6-8日内发货
20 μg
¥ 1,530
5日内发货
50 μg
¥ 2,970
5日内发货
100 μg
¥ 5,180
5日内发货
200 μg
¥ 9,390
5日内发货
500 μg
¥ 20,700
5日内发货
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产品介绍


生物活性
产品描述
TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.
生物活性
Immobilized Human NKG2D, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human MICA, His Tag with the EC50 of 0.32μg/ml determined by ELISA.
研究背景
TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号Q96QC4
蛋白构建Glu24-Gln308
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名PERB11.1, MICA, MGC21250, MGC111087, FLJ60820, FLJ36918, DAMA-345G11.2
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量35.8 kDa (predicted). Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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  • 重组蛋白稀释 计算器
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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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