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Anti-EMMPRIN/CD147 Antibody-FITC (2T794)
还可以产品编号 TMAY-00422F
Anti-EMMPRIN/CD147 Antibody-FITC (2T794) 是一种 FITC-conjugated Rabbit 抗体，靶向 EMMPRIN/CD147。Anti-EMMPRIN/CD147 Antibody-FITC (2T794) 可用于 FCM。
Anti-EMMPRIN/CD147 Antibody-FITC (2T794)
Anti-EMMPRIN/CD147 Antibody-FITC (2T794)
还可以产品编号 TMAY-00422F
Anti-EMMPRIN/CD147 Antibody-FITC (2T794) 是一种 FITC-conjugated Rabbit 抗体，靶向 EMMPRIN/CD147。Anti-EMMPRIN/CD147 Antibody-FITC (2T794) 可用于 FCM。
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| 产品描述 | Anti-EMMPRIN/CD147 Antibody-FITC (2T794) is a FITC-conjugated Rabbit antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody-FITC (2T794) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2T794 |
| 交叉反应 | Human |
| 验证活性 | 1. Profile of peripheral blood lymphocytes analyzed by flow cytometry. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable lymphocytes. 2. Profile of anti-CD147 reactivity on HeLa cells, PC-3 cells, A549 cells analyzed by flow cytometry. 3. Immunofluorescence staining of human CD147 in HeLa cells with rabbit monoclonal antibody (5 µg/mL). The image showing membrane staining of HeLa cells. Primary antibody (FITC conjugated) was incubated for 1 hour at 37°C. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD147 / Basigin (rh CD147; NP_940991.1Met 1-His 205) and conjugated with FITC under optimum conditions, the unreacted FITC was removed . |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD147 protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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