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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-E3 ubiquitin ligase Polyclonal Antibody

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货号 TMAB-05398

Anti-E3 ubiquitin ligase Polyclonal Antibody 是一种 Rabbit 抗体，靶向 E3 ubiquitin ligase。Anti-E3 ubiquitin ligase Polyclonal Antibody 可用于 WB。

Anti-E3 ubiquitin ligase Polyclonal Antibody

Anti-E3 ubiquitin ligase Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05398

Anti-E3 ubiquitin ligase Polyclonal Antibody 是一种 Rabbit 抗体，靶向 E3 ubiquitin ligase。Anti-E3 ubiquitin ligase Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-E3 ubiquitin ligase Polyclonal Antibody is a Rabbit antibody targeting E3 ubiquitin ligase. Anti-E3 ubiquitin ligase Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion outer membrane; Multi-pass membrane protein. Peroxisome. Note: Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome.
组织特异性Widely expressed with highest levels in the heart, skeletal muscle, placenta, kidney and liver. Barely detectable in colon and thymus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
抗原信息
免疫原
KLH conjugated synthetic peptide: human E3 ubiquitin ligase/RNF218
抗原种属
Human
基因名称
MUL1
基因ID
79594
蛋白名称
Mitochondrial ubiquitin ligase activator of NFKB 1
Uniprot ID
Q969V5
功能
Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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