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Anti-Phospho-LRRK2 (Thr1410) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-LRRK2 (Thr1410)。Anti-Phospho-LRRK2 (Thr1410) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-LRRK2 (Thr1410) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-LRRK2 (Thr1410)。Anti-Phospho-LRRK2 (Thr1410) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Phospho-LRRK2 (Thr1410) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LRRK2 (Thr1410). Anti-Phospho-LRRK2 (Thr1410) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Membrane. Mitochondrion. Localized in the cytoplasm and associated with cellular membrane structures. Associates with the mitochondrial outer membrane. |
| 组织特异性 | Expressed throughout the adult brain, but at a lower level than in heart and liver. Also expressed in placenta, lung, skeletal muscle, kidney and pancreas. In the brain, expressed in the cerebellum, cerebral cortex, medulla, spinal cord occipital pole, frontal lobe, temporal lobe and putamen. Expression is particularly high in brain dopaminoceptive areas. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | LRRK2 (Dardarin) is encoded by the gene LRRK2. Genetic mutations of LRRK2 have been linked to Parkinsonism and synucleinopathies. LRRK2 belongs to the ROCO protein family and includes a protein kinase domain of the MAPKKK class and several other major functional domains. |
| 免疫原 | KLH conjugated synthesised phosphopeptide: human LRRK2 around the phosphorylation site of Thr1410 |
| 抗原种属 | Human |
| 基因名称 | LRRK2 |
| 基因ID | |
| 蛋白名称 | Leucine-rich repeat serine/threonine-protein kinase 2 |
| Uniprot ID | |
| 功能 | May play a role in the phosphorylation of proteins central to Parkinson disease. Phosphorylates PRDX3. May also have GTPase activity. |
| 分子量 | Theoretical: 286 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |