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Anti-NMDAR3A Polyclonal Antibody
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产品编号 TMAB-01249
Anti-NMDAR3A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NMDAR3A。Anti-NMDAR3A Polyclonal Antibody 可用于 WB。
Anti-NMDAR3A Polyclonal Antibody
Anti-NMDAR3A Polyclonal Antibody
还可以产品编号 TMAB-01249
Anti-NMDAR3A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NMDAR3A。Anti-NMDAR3A Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-NMDAR3A Polyclonal Antibody is a Rabbit antibody targeting NMDAR3A. Anti-NMDAR3A Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Human,Rat,Dog,Rabbit) |
| 验证活性 | 1. Sample: Placenta (Mouse) lysate at 40 μg Primary: Anti-NMDAR3a (TMAB-01249) at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 123 kDa Observed band size: 123 kDa 2. Sample: Testis (Mouse) Lysate at 40 μg Primary: Anti-NMDAR3A (TMAB-01249) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 123 kDa Observed band size: 123 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. Requires the presence of GRIN1 to be targeted at the plasma membrane |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neuro-degeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to 7. The kainate/AMPA receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas the NMDA receptors exhibit slow kinesis of Ca2+ ions and a high permeability for Ca2+ ions. One such NMDA receptor, NR3B, is expressed in motor neurons and forms cation channels impermeable to calcium, which can resist many open-channel blockers. NR3B functions in the brain as an excitatory glycine receptor, modifying the normal role of glycine as an inhibitory neurotransmitter. |
| 免疫原 | KLH conjugated synthetic peptide: human NMDAR3A/NR3A |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | NMDA Receptors |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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