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顶部生物活性储存和溶解信息计算器

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2

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产品编号 TMAC-00177

别名 RUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435), p-RUNX1 (S435)

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-RUNX1 (Ser435)。Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 可用于 WB。

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 2

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产品编号 TMAC-00177 别名 RUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435), p-RUNX1 (S435)

Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-RUNX1 (Ser435)。Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
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100 μL
¥ 2,230
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产品介绍

生物活性
产品描述
Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RUNX1 (Ser435). Anti-Phospho-RUNX1 (Ser435) Polyclonal Antibody can be used in WB.
别名RUNX1 (p-Ser435), RUNX1 (p-S435), p-RUNX1 (Ser435), p-RUNX1 (S435)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extracts from 293 cells (Lane 2), HeLa cells (Lane 3) and HepG2 cells (Lane 4), using AML1 (Phospho-Ser435) Antibody TMAC-00177. The lane on the left is treated with antigen-specific peptide.
verifiedActivity
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of Serine 435( S-N-S(p)-P-T) derived from Human AML1
抗原种属
human
Uniprot ID
Q01196
化学信息
分子量Actual: 53 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

RUNX1 (pSer435)RUNX1 (pS435)RUNX1 (phospho-Ser435)RUNX1 (phospho-S435)pRUNX1 (Ser435)pRUNX1 (S435)

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4个月前
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