Name: Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-00359
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 313

6-8日内发货

10 μg

¥ 498

6-8日内发货

20 μg

¥ 793

5日内发货

50 μg

¥ 1,580

5日内发货

100 μg

¥ 2,660

5日内发货

200 μg

¥ 4,790

5日内发货

500 μg

¥ 10,600

5日内发货

生物活性

产品描述	Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.
生物活性	Immobilized Human Endoglin, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Endoglin Antibody, hFc Tag with the EC50 of 9.4ng/ml determined by ELISA.
研究背景	Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	P17813-1
蛋白构建	Glu26-Gly586
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	ORW1, ORW, HHT1, ENG, Endoglin, END, CD105
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	63.7 kDa (predicted). Due to glycosylation, the protein migrates to 70-82 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Endoglin/CD105 Protein, Human, Recombinant (His & Avi)

Endoglin/CD105 Protein, Human, Recombinant (His & Avi)

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