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Anti-IGF2R/M6PR Antibody (1F622)

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货号 TMAB-07548

Anti-IGF2R/M6PR Antibody (1F622) 是一种 Rabbit 抗体,靶向 IGF2R/M6PR。Anti-IGF2R/M6PR Antibody (1F622) 可用于 WB。

Anti-IGF2R/M6PR Antibody (1F622)

Anti-IGF2R/M6PR Antibody (1F622)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07548

Anti-IGF2R/M6PR Antibody (1F622) 是一种 Rabbit 抗体,靶向 IGF2R/M6PR。Anti-IGF2R/M6PR Antibody (1F622) 可用于 WB。

规格价格库存数量
25 μL
¥ 795
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50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-IGF2R/M6PR Antibody (1F622) is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Antibody (1F622) can be used in WB.
Ig Type
IgG
克隆号
1F622
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Lysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IGF2R
抗原种属
Human
基因名称
IGF2R
基因ID
蛋白名称
Cation-independent mannose-6-phosphate receptor
Uniprot ID
功能
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
化学信息
分子量Theoretical: 300 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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