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Anti-IGF2R/M6PR Antibody (1F622) 是一种 Rabbit 抗体,靶向 IGF2R/M6PR。Anti-IGF2R/M6PR Antibody (1F622) 可用于 WB。
Anti-IGF2R/M6PR Antibody (1F622) 是一种 Rabbit 抗体,靶向 IGF2R/M6PR。Anti-IGF2R/M6PR Antibody (1F622) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-IGF2R/M6PR Antibody (1F622) is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Antibody (1F622) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 1F622 |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Lysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | PBS, Glycerol, BSA. |
| 浓度 | 1mg/ml |
| 研究背景 | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
| 免疫原 | KLH conjugated synthetic peptide: human IGF2R |
| 抗原种属 | Human |
| 基因名称 | IGF2R |
| 基因ID | |
| 蛋白名称 | Cation-independent mannose-6-phosphate receptor |
| Uniprot ID | |
| 功能 | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
| 分子量 | Theoretical: 300 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |