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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FRY/C13orf14 Polyclonal Antibody

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货号 TMAB-06180

Anti-FRY/C13orf14 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FRY/C13orf14。Anti-FRY/C13orf14 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-FRY/C13orf14 Polyclonal Antibody

Anti-FRY/C13orf14 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06180

Anti-FRY/C13orf14 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FRY/C13orf14。Anti-FRY/C13orf14 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-FRY/C13orf14 Polyclonal Antibody is a Rabbit antibody targeting FRY/C13orf14. Anti-FRY/C13orf14 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed diffusely throughout the cytoplasm in interphase. Localizes to the separating centrosomes in prophase, to the spindle poles and spindle microtubules in prometaphase to metaphase, to spindle microtubules in anaphase and to the distal sections of the midbody in cytokinesis. Colocalizes with PLK1 to separating centrosomes and spindle poles from prophase to metaphase in mitosis, but not in other stages of the cell cycle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景In yeast, flies, and worms, the Dbf2-related (Ndr) kinase protein family functions in various aspects of cell polarity and morphogenesis. The Drosophila melanogaster protein, furry, is responsible for maintaining integrity of polarized cell extensions, such as epidermal hair cells, lateral extensions of the arista and the shafts of neuronal sensory bristles. Mutations in furry lead to the formation of branched arista laterals, bristles and hairs. The yeast homolog of furry, Mor2, is important for the localization of F-actin specifically at the cell ends and is required for the restriction of the growth zones. The mammalian homolog of the Drosophila furry protein is FRY, also known as C13orf14, a 3,013 amino acid protein that probably functions as a transcription factor for genes that regulate the actin cytoskeleton. The gene encoding FRY maps to chromosome 13, which comprises nearly 4% of human DNA and contains around 114 million base pairs and 400 genes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FRY/C13orf14
抗原种属
Human
基因名称
FRY
基因ID
10129
蛋白名称
Protein furry homolog
Uniprot ID
Q5TBA9
功能
Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation.
化学信息
分子量Theoretical: 339 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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