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Anti-Osteoprotegerin Antibody (7E614)
还可以产品编号 TMAY-00543
Anti-Osteoprotegerin Antibody (7E614) 是一种 Rabbit 抗体，靶向 Osteoprotegerin。Anti-Osteoprotegerin Antibody (7E614) 可用于 ELISA。
Anti-Osteoprotegerin Antibody (7E614)
Anti-Osteoprotegerin Antibody (7E614)
还可以产品编号 TMAY-00543
Anti-Osteoprotegerin Antibody (7E614) 是一种 Rabbit 抗体，靶向 Osteoprotegerin。Anti-Osteoprotegerin Antibody (7E614) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Osteoprotegerin Antibody (7E614) is a Rabbit antibody targeting Osteoprotegerin. Anti-Osteoprotegerin Antibody (7E614) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7E614 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Osteoprotegerin / TNFRSF11B (rh Osteoprotegerin / TNFRSF11B; TMPY-01724; NP_002537.3; Met 1-Leu 401). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Osteoprotegerin or TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. Osteoprotegerin/TNFRSF11B acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. This protein may inhibit the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. Osteoprotegerin/TNFRSF11B also play a role in preventing arterial calcification, act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Osteoprotegerin / TNFRSF11B protein (TMPY-01724) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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