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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-ABL2 Monoclonal Antibody (6I252)

Synonyms: FLJ41441, FLJ31718, FLJ22224, ARG, ABLL
货号 TMAT-0011 一键复制产品信息
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Anti-ABL2 Monoclonal Antibody (6I252) 是一种 Mouse 抗体，靶向 ABL2。Anti-ABL2 Monoclonal Antibody (6I252) 可用于 IF。

Anti-ABL2 Monoclonal Antibody (6I252)

一键复制产品信息
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货号 TMAT-0011

别名 FLJ41441, FLJ31718, FLJ22224, ARG, ABLL

Anti-ABL2 Monoclonal Antibody (6I252) 是一种 Mouse 抗体，靶向 ABL2。Anti-ABL2 Monoclonal Antibody (6I252) 可用于 IF。

Anti-ABL2 Monoclonal Antibody (6I252)
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产品介绍

生物活性
产品描述
Anti-ABL2 Monoclonal Antibody (6I252) is a Mouse antibody targeting ABL2. Anti-ABL2 Monoclonal Antibody (6I252) can be used in IF.
别名
FLJ41441, FLJ31718, FLJ22224, ARG, ABLL
Ig Type
IgG1
克隆号
6I252
反应种属
Human,Mouse
应用IF
推荐剂量
IF: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89%, 90 and 93% identity in their SH3, SH2 and tyrosine domain, but only 29% identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of ABL2 expressed in E. Coli.
抗原种属
Human
基因名称
ABL2
基因ID
27
蛋白名称
Tyrosine-protein kinase ABL2
Uniprot ID
P42684
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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