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Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) 是一种 Mouse 抗体,靶向 Phospho-PTK2 (Ser 722)。Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) 可用于 WB,IP,IF,IHC-P。
Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) 是一种 Mouse 抗体,靶向 Phospho-PTK2 (Ser 722)。Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) 可用于 WB,IP,IF,IHC-P。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) is a Mouse antibody targeting Phospho-PTK2 (Ser 722). Anti-Phospho-PTK2 (Ser 722) Antibody (7J439) can be used in WB,IP,IF,IHC-P. |
别名 | PTK2 (p-Ser 722), PTK2 (p-S 722), p-PTK2 (Ser 722), p-PTK2 (S 722) |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. A.Western blot analysis of FAK phosphorylation in non-transfected:(A,D), untreated human FAK transfected:(B,E) and lambda protein phosphatase treated human FAK transfected:(C,F) 293T whole cell lysates. Antibodies tested include p-FAK (A-12):(A,B,C) and FAK (C-903):(D,E,F). 2. B.Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing cytoplasmic staining of glandular cells. |
应用 | |
推荐剂量 | WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Activation of integrins in the extracellular matrix (ECM) of eukaryotic cells promotes the formation of membrane adhesion complexes, known as focal adhesions, which can include cytoskeletal proteins and protein tyrosine kinases, such as focal adhesion kinase (FAK). Phosphorylation events occurring within focal adhesions influence numerous processes that include mitogenic signaling, cell survival and cell motility. FAK is a non-receptor tyrosine kinase that is ubiquitously expressed and highly conserved between species. FAK is recruited by integrin clusters and variably phosphorylated depending on the effector molecules present in the focal adhesion. Phospho-rylation of FAK Tyr 397 decreases during serum starvation, contact inhibition and cell cycle arrest, all conditions under which activating FAK Tyr 407 phosphorylation increases. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide |
Uniprot ID |
分子量 | Theoretical: 125 kDa. |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. |
运输方式 | Shipping with blue ice. |
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