L-NIO dihydrochloride

Name: L-NIO dihydrochloride
Brand: TargetMol
SKU: T11806
Rating: 4.5 (1 reviews)

还可以

产品编号 T11806Cas号 159190-44-0

L-NIO dihydrochloride induces a consistentfocal ischemic infarctin rats. L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively.

L-NIO dihydrochloride

还可以

产品编号 T11806Cas号 159190-44-0

规格	价格	库存	数量
100 mg	¥ 5,850	6-8周

大包装 & 定制

加入购物车

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

L-NIO dihydrochloride 相关产品

产品介绍

生物活性

产品描述	L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.
靶点活性	eNOS:3.9 μM (ki), iNOS:3.9 μM (ki), nNOS:ki： 1.7 μM
体外活性	L-NIO is a non-selective,potent and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively.
体内活性	L-NIO ?causes focal cerebral ischemia in the adult rat brain.

化学信息

分子量	209.67
分子式	C₇H₁₆ClN₃O₂
CAS No.	159190-44-0
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 33.33 mg/mL (135.42 mM), Sonication is recommended.

H2O: 50 mg/mL (203.14 mM), Sonication is recommended.

溶液配制表

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	4.7694 mL	23.8470 mL	47.6940 mL	238.4700 mL
5 mM	0.9539 mL	4.7694 mL	9.5388 mL	47.6940 mL
10 mM	0.4769 mL	2.3847 mL	4.7694 mL	23.8470 mL
20 mM	0.2385 mL	1.1923 mL	2.3847 mL	11.9235 mL
50 mM	0.0954 mL	0.4769 mL	0.9539 mL	4.7694 mL
100 mM	0.0477 mL	0.2385 mL	0.4769 mL	2.3847 mL