Name: CD161 Protein, Human, Recombinant (C-hFc)
Brand: TargetMol
SKU: TMPJ-01094
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 693

6-8日内发货

10 μg

¥ 1,170

6-8日内发货

20 μg

¥ 1,860

5日内发货

50 μg

¥ 3,470

5日内发货

100 μg

¥ 4,930

5日内发货

200 μg

¥ 7,350

5日内发货

500 μg

¥ 12,100

5日内发货

1 mg

¥ 18,900

5日内发货

生物活性

产品描述	CD161 Protein, Human, Recombinant (C-hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-70 KDa and the accession number is Q12918.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Killer cell lectin-like receptor subfamily B, member 1(KLRB1) is a single-pass type II membrane protein which contains 1 C-type lectin domain. KLRB1 plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. It acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q12918
氨基酸序列	Gln67-Ser225
蛋白构建	Gln67-Ser225
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. Greater than 81% as determined by SEC-HPLC. (QC verified)
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	NKR-P1A, NKRP1A, Natural killer cell surface protein P1A, KLRB1, Killer cell lectin-like receptor subfamily B member 1, HNKR-P1a, C-type lectin domain family 5 member B, CLEC5B, CD161
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.

化学信息

分子量	55-70 KDa (reducing condition)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CD161 Protein, Human, Recombinant (C-hFc)

CD161 Protein, Human, Recombinant (C-hFc)

产品介绍

计算器

剂量转换

引用文献

技术支持

关键词