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GITR/TNFRSF18 Protein, Human, Recombinant (His)

GITR/TNFRSF18 Protein, Human, Recombinant (His)

产品编号 TMPY-00072
别名: AITR, GITR-D, tumor necrosis factor receptor superfamily, member 18, CD357, GITR

GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.

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TargetMol
GITR/TNFRSF18 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 2,930 现货
200 μg ¥ 5,320 5日内发货
500 μg ¥ 11,630 5日内发货
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产品目录号及名称: GITR/TNFRSF18 Protein, Human, Recombinant (His) (TMPY-00072)
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生物活性
技术参数
产品性质
参考文献
生物活性 Measured by its binding ability in a functional ELISA. Immobilized TNFRSF18-His at 10 μg/mL (100 μL/well) can bind TNFSF18-mFc , the EC50 of TNFSF18-mFc is 20-60 ng/mL.

TargetMol Bioactive

产品描述 GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 Q9Y5U5-3
别名 AITR, GITR-D, tumor necrosis factor receptor superfamily, member 18, CD357, GITR
蛋白构建 The Human TNFRSF18 (NP_683700.1) (Met1-Glu161) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE.

TargetMol

分子量 16 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy

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Keywords

GITR/TNFRSF18 Protein, Human, Recombinant (His) AITR GITR-D tumor necrosis factor receptor superfamily, member 18 CD 357 CD-357 CD357 GITR recombinant recombinant-proteins proteins protein

 

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