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顶部生物活性储存和溶解信息计算器

Anti-CD200 Antibody (2H839)

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Anti-CD200 Antibody (2H839)
产品编号 TMAY-03079
别名 OX-2, OX2, MRC, MOX2, MOX1, Cd200 molecule

Anti-CD200 Antibody (2H839) 是一种 Rabbit 抗体，靶向 CD200。Anti-CD200 Antibody (2H839) 可用于 FCM。

Anti-CD200 Antibody (2H839)
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Anti-CD200 Antibody (2H839)

Rating icon 还可以
Anti-CD200 Antibody (2H839)
产品编号 TMAY-03079 别名 OX-2, OX2, MRC, MOX2, MOX1, Cd200 molecule

Anti-CD200 Antibody (2H839) 是一种 Rabbit 抗体，靶向 CD200。Anti-CD200 Antibody (2H839) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD200 Antibody (2H839) is a Rabbit antibody targeting CD200. Anti-CD200 Antibody (2H839) can be used in FCM.
别名OX-2, OX2, MRC, MOX2, MOX1, Cd200 molecule
Ig Type
Rabbit IgG
克隆号
2H839
交叉反应
Mouse
验证活性
Flow cytometric analysis of CD200 expression on spleen lymphocytes. BALB/c splenocytes were stained with Mouse CD200 Monoclonal Ab, then a FITC-conjugated second step antibody. The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD200 (rM CD200; TMPY-01160; O54901.1; Met 1-Gly 232).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through the CD200:CD200R axis have been shown to play an important role in the regulation of anti-tumor immunity, and overexpression of CD200 has been reported in a number of malignancies, including CLL, as well as on cancer stem cells. The role of CD200-CD200R signaling in immune regulation of the central nervous system has become a popular field of research in recent years. Many studies have shown that there is a close correlation between CD200-CD200R, microglia activation, and Parkinson's disease (PD). The ability of CD200 to suppress myeloid cell activation is critical for maintaining normal tissue homeostasis but may also enhance the survival of migratory neoplastic cells. CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 has been characterized as an important immunoregulatory molecule, increased expression of which can lead to decreased transplant rejection, autoimmunity, and allergic disease. Elevated CD200 expression has been reported to be associated with poor prognosis in some human malignancies. Besides, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Mouse CD200 protein (50074-M08H)
抗原种属
Mouse
研究领域
Neuroinflammation, Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

OX 2MOX-2MOX-1MOX 2MOX 1

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