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Anti-IGF2BP2 Polyclonal Antibody

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货号 TMAB-07543

Anti-IGF2BP2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IGF2BP2。Anti-IGF2BP2 Polyclonal Antibody 可用于 WB。

Anti-IGF2BP2 Polyclonal Antibody

Anti-IGF2BP2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07543

Anti-IGF2BP2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IGF2BP2。Anti-IGF2BP2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍


生物活性
产品描述
Anti-IGF2BP2 Polyclonal Antibody is a Rabbit antibody targeting IGF2BP2. Anti-IGF2BP2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa.
组织特异性Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景IGF2BP2 (insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type 2 diabetes mellitus.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IGF2BP2/IMP2
抗原种属
Human
基因名称
IGF2BP2
基因ID
蛋白名称
Insulin-like growth factor 2 mRNA-binding protein 2
Uniprot ID
功能
Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs.
化学信息
分子量Theoretical: 66 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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