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Reston ebolavirus (REBOV) (strain Philippines-96) Nucleoprotein/NP Protein (His & SUMO)

Reston ebolavirus (REBOV) (strain Philippines-96) Nucleoprotein/NP Protein (His & SUMO)

产品编号 TMPH-03405

Reston ebolavirus (REBOV) (strain Philippines-96) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.3 kDa and the accession number is Q91DE1.

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Reston ebolavirus (REBOV) (strain Philippines-96) Nucleoprotein/NP Protein (His & SUMO)
规格 价格/CNY 货期 数量
20 μg ¥ 2,290 20日内发货
100 μg ¥ 4,320 20日内发货
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产品目录号及名称: Reston ebolavirus (REBOV) (strain Philippines-96) Nucleoprotein/NP Protein (His & SUMO) (TMPH-03405)
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产品描述 Reston ebolavirus (REBOV) (strain Philippines-96) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.3 kDa and the accession number is Q91DE1.
种属 REBOV
表达系统 E. coli
标签 N-6xHis-SUMO
蛋白编号 Q91DE1
氨基酸序列 RPNLGSRQDDDNEIPFPGPISNNPDQDHLEDDPRDSRDTIIPNSAIDPEDGDFENYNGYHDDEVGTAGDLVLFDLDDHEDDNKAFELQDSSPQSQREIERERLIHPPPGNNKDDNRASDNNQQSADSEEQEGQYNRHRGPERTTANRRLSPVHEEDTPIDQGDDDPSSPPPLESDDDDASSSQQDPDYTAVAPPAPVYRSAEAHEPPHKSSNEPAETSQLNEDPDIGQSKSMQKLGETYHHLLRTQGPFEAINYYHMMKDEPVIFSTDDGKEYTYPDSLEEAYPPWLTEKERLDNENRYIYINNQQFFWPVMSPRDKFLAILQHHQ
蛋白构建 414-739 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 53.3 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Oligomerizes into helical capsid to encapsidate the viral genome, protecting it from nucleases and the cellular innate immune response. VP35 binds to and stabilizes monomeric NP, keeping it soluble. Upon virus replication, NP is recruited to bind cooperatively viral genomic RNA and VP35 is released. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. The nucleocapsid is helical with a pitch of 10.81 NP per turn and a diameter of about 22nm. Each NP binds to six nucleotides of viral genomic RNA, three being exposed to the solvant and three hidden into the nucleocapsid. Recruits also host PPP2R5C phosphatase to dephosphorylate VP30 and thereby promote viral transcription. Upon virion assembly and budding, NP binds to VP24 and possibly host STAU1.

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Keywords

recombinant recombinant-proteins proteins protein

 

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