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Anti-TNF alpha Antibody (4V549)
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产品编号 TMAB-01869
Anti-TNF alpha Antibody (4V549) 是一种 Mouse 抗体，靶向 TNF alpha。Anti-TNF alpha Antibody (4V549) 可用于 WB。
Anti-TNF alpha Antibody (4V549)
Anti-TNF alpha Antibody (4V549)
还可以产品编号 TMAB-01869
Anti-TNF alpha Antibody (4V549) 是一种 Mouse 抗体，靶向 TNF alpha。Anti-TNF alpha Antibody (4V549) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-TNF alpha Antibody (4V549) is a Mouse antibody targeting TNF alpha. Anti-TNF alpha Antibody (4V549) can be used in WB. |
| Ig Type | IgG1 |
| 克隆号 | 4V549 |
| 交叉反应 | Human |
| 验证活性 | THP-1 (H) cells were treated with or without LPS (100 ng/ml) for 16 h and Brefeldin A (5 µg/ml) for 4 h, 25 μg total protein per Lane of cell lysates probed with TNF alpha monoclonal antibody, unconjugated (TMAB-01869) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor, membrane form: Membrane; Single-pass type II membrane protein. Tumor necrosis factor, soluble form: Secreted. C-domain 1: Secreted. C-domain 2: Secreted. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020] |
| 免疫原 | Recombinant Protein: human TNF alpha 77-233aa |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | TNF,Inflammatory mediators,TNF Superfamily,Metabolic disorders,SARS Coronavirus,TNF |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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