Nectin-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 64.08 kDa and the accession number is Q92692-2.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
20 μg | ¥ 2,940 | 5日内发货 | ||
100 μg | ¥ 6,800 | 5日内发货 |
生物活性 | Measured by its binding ability in a functional ELISA. Immobilized Human PVRIG hFc at 2 μg/mL (100 μL/well) can bind Human Nectin-2 (ECD, hFc & AVI Tag), Biotinylated, the EC50 of Human Nectin-2 (ECD, hFc & AVI Tag), Biotinylated is 10-60 ng/mL. |
产品描述 | Nectin-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 64.08 kDa and the accession number is Q92692-2. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-hFc-Avi |
蛋白编号 | Q92692-2 |
别名 | Nectin-2, HVEB, PVRR2, CD112, PRR2, poliovirus receptor-related 2 (herpesvirus entry mediator B) |
蛋白构建 | The Human NECTIN2 (NP_002847.1)(Met1-Leu360) was expressed with a c-terminal AVI tagged Fc region of Human IgG1 at the C-terminus (Fc-AVI). The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. |
蛋白纯度 | ≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. |
分子量 | 64.08 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy. |
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Nectin-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated PVRR 2 herpesvirus entry mediator B poliovirus receptor-related 2 PRR 2 CD 112 Nectin-2 HVEB PVRR2 PVRR-2 CD112 PRR-2 PRR2 poliovirus receptor-related 2 (herpesvirus entry mediator B) CD-112 recombinant recombinant-proteins proteins protein