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- 3840种天然产物的独特集合，可用于高通量筛选和高内涵筛选；
- 提供产品的生物学信息和药物学信息，为筛选提供理论方向和研究基础；
- 来源清晰：精选来自动物、植物、微生物的已知活性天然产物；更具体到植物种属，并标注准确英文名与拉丁名，方便您的后期研究确证；
- 结构多样性好：含黄酮类、生物碱类在内的多种化合物类型，拥有详细的分类信息；
- NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。
天然产物库
Natural Product Library
很棒天然产物在化学结构和生物活性多样性方面的优势，使其在新药研发中具有不可替代的重要地位。近年来提取分离和结构鉴定技术的快速发展, 大大提高了从天然产物中开发新药的效率和成功率。据统计，1981年至 2019年所有上市的药物中，有近2/3的药物在不同程度上都与天然产物相关。我国近50年自研成功的新药90%以上与天然产物有关。 然而，长期困扰天然产物药物筛选的问题之一是，得到天然产物苗头化合物进行后继的药理实验时，天然产物的成本太高。为了一定程度上帮助研发人员避免这个问题，TargetMol 推出L6010天然产物库，收集 3840 种天然产物单体，广泛涉及1800种植物来源。在筛得阳性化合物以后，您从自然界或者天然产物全合成中得到此产品大包装的难度更小，更能满足您对于苗头化合物进行深入研究时成本控制的需求。
TargetMol 的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。
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化合物库相关信息
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天然产物库规格
- 1 mg
- 30 μL x 10 mM (in DMSO)
- 50 μL x 10 mM (in DMSO)
- 100 μL x 10 mM (in DMSO)
- 250 μL x 10 mM (in DMSO)
询价 & 定制
产品描述
包装和储存
- 可选用DMSO耐受的96/384孔板或2D 条形码编码管；
- 干粉蓝冰运输，DMSO溶液干冰运输；
- 排布：96孔板：1st & 12th 空白对照，384孔板：1st & 2nd & 23th & 24th空白对照。
- 本化合物库通常以 DMSO 10 mM 浓度提供。少量产品可能因溶解性或稳定性需求，采用其他溶剂或浓度包装，具体以实际产品信息为准。
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化合物库组成
Endogenous Metabolite
Apoptosis
Antibacterial
Autophagy
NF-κB
Antibiotic
Antioxidant
Antifungal
Reactive Oxygen Species
Parasite
COX
Influenza Virus
Cytochromes P450
TNF
AChR
DNA/RNA Synthesis
Calcium Channel
GABA Receptor
NO Synthase
HIV Protease
Cholinesterase (ChE)
PPAR
Caspase
p38 MAPK
ERK
IL Receptor
Akt
Anti-infection
Tyrosinase
STAT
Virus Protease
AMPK
Dehydrogenase
ROS
MMP
Ferroptosis
PKC
Nrf2
Estrogen/progestogen Receptor
Topoisomerase
Microtubule Associated
Estrogen Receptor/ERR
5-HT Receptor
PI3K
Potassium Channel
Adrenergic Receptor
Lipoxygenase
HSV
Bcl-2 Family
Antiviral
ATPase
NOS
Beta Amyloid
Sodium Channel
TRP/TRPV Channel
Immunology/Inflammation related
Glucosidase
Antifection
JNK
Mitophagy
Wnt/beta-catenin
PARP
PDE
EGFR
Drug Metabolite
NMDAR
P-gp
Prostaglandin Receptor
HBV
Nucleoside Antimetabolite/Analog
MAO
HIF/HIF Prolyl-Hydroxylase
Amino Acids and Derivatives
Phosphatase
iGluR
GluR
SARS-CoV
TLR
ribosome
Dopamine Receptor
TGF-beta/Smad
HDAC
Reductase
Mitochondrial Metabolism
mTOR
Interleukin
Phospholipase
HCV Protease
Adenosine Receptor
Opioid Receptor
JAK
GPCR
RAAS
Glucocorticoid Receptor
MAPK
Histamine Receptor
Androgen Receptor
Sirtuin
transporter
p53
FXR
VEGFR
CDK
HSP
IκB/IKK
HIF
Cannabinoid Receptor
NOD
Monoamine Oxidase
PKA
Aryl Hydrocarbon Receptor
Gamma-secretase
Platelet aggregation
HMG-CoA Reductase
ADC Cytotoxin
Chloride channel
Carbonic Anhydrase
Transferase
Arginase
BACE
UGT
LDL
Fatty Acid Synthase
FAAH
Reverse Transcriptase
MEK
AhR
GSK-3
Tyrosine Kinases
Serine Protease
Xanthine Oxidase
Epigenetic Reader Domain
IGF-1R
DNA
Indoleamine 2,3-Dioxygenase (IDO)
Lipid
Free radical scavengers
Aromatase
Proteasome
ROR
Integrin
c-Met/HGFR
NADPH
MRP
Serine/threonin kinase
IAP
E1/E2/E3 Enzyme
PAFR
DNA gyrase
ABC Transporter
CaMK
Beta-Secretase
PGE Synthase
Aminopeptidase
GPCR19
PDK
FAK
NOD-like Receptor (NLR)
Thyroid hormone receptor(THR)
Proton pump
P2Y Receptor
LTR
Glutathione Peroxidase
Progesterone Receptor
c-Myc
Serotonin Transporter
Cell Cycle Arrest
Cysteine Protease
Liver X Receptor
Amylase
Bcr-Abl
Phosphorylase
P2X Receptor
Smo
Hedgehog/Smoothened
CCR
CXCR
PTEN
cAMP
Telomerase
SGLT
ATP Citrate Lyase
Trk receptor
Retinoid Receptor
FGFR
Syk
S6 Kinase
Imidazoline Receptor
MicroRNA
DHFR
Src
DNA Alkylator/Crosslinker
Histone Demethylase
Lipase
gp120/CD4
OCT
Pim
Antifolate
Leukotriene Receptor
Glucokinase
RANKL/RANK
Adiponectin Receptor
Monoamine Transporter
PDGFR
Bombesin Receptor
PAK
Aurora Kinase
OAT
Acyltransferase
Histone Acetyltransferase
Decarboxylase
PAI-1
Pyroptosis
RSV
Casein Kinase
ATM/ATR
GST
NADPH-oxidase
DNA Methyltransferase
IRAK
Ras
Thrombin
HER
S1P Receptor
Vitamin
FOXO3
Advanced Glycation End Products
Mdm2
Adenylyl Cyclase
Transaminase
NPC1L1
Monocarboxylate transporter
stilbene oxidase
Hydrogenase
RAR/RXR
CD38
CYP19A1
Histone Methyltransferase
Dynamin
MyD88
LPL Receptor
IFNAR
Aconitase
DYRK
Cell wall
PERK
Factor Xa
Melatonin Receptor
CaSR
Glutaminase
IDO
Prolyl Endopeptidase (PREP)
IRE1
Annexin A
MTH1
Fas/FasL
MT Receptor
Glucagon Receptor
GlyT
Hexokinase
DPP-4
Stearoyl-CoA Desaturase (SCD)
Bradykinin Receptor
Angiotensin-converting Enzyme (ACE)
Somatostatin
Thrombopoietin Receptor
Norepinephrine
BCRP
Glutathione reductase
Survivin
CPT
GluCls
hCE
ALK
CRISPR/Cas9
Oxytocin Receptor
Adenosine Deaminase
PLK
Complement System
ATTECs
Neurokinin receptor
NMU2R
FLT
ROS Kinase
CFTR
PD-1/PD-L1
PKM
化合物库信息
| Empty | 99-96-7 | 99-94-5 | 99-93-4 | 99910-50-6 | 99-86-5 | 99-76-3 | 997-55-7 | 99-66-1 | 99-50-3 | 99-48-9 | Empty |
| 4-Hydroxybenzoic acid | p-Toluic Acid | 4-Hydroxyacetophenone | 4,6-Dibromoindole | α-Terpinene | Methyl Paraben | N-Acetyl-L-aspartic acid | Valproic Acid | Protocatechuic acid | Carveol | ||
| Empty | 99365-23-8 | 99353-00-1 | 99-32-1 | 99291-20-0 | 99-24-1 | 99-20-7 | 99-14-9 | 99-10-5 | 99-06-9 | 98-98-6 | Empty |
| Prosaikogenin G | Methyl rosmarinate | Chelidonic acid | V-9-M Cholecystokinin nonapeptide | Methyl gallate | D-(+)-Trehalose | Tricarballylic acid | 3,5-Dihydroxybenzoic acid | 3-Hydroxybenzoic acid | PCL 016 | ||
| Empty | 98985-24-1 | 989-51-5 | 98891-44-2 | 98891-41-9 | 98-86-2 | 98-79-3 | 987-78-0 | 987-65-5 | 98665-22-6 | 98-55-5 | Empty |
| yibeinoside A | (-)-Epigallocatechin Gallate | Pseudolaric acid A-O-β-D-glucopyranoside | Pseudolaric acid B β-D-glucoside | Acetophenone | L-Pyroglutamic acid | Citicoline | ATP disodium salt | Ganoderic acid G | α-Terpineol | ||
| Empty | 98474-74-9 | 982-57-0 | 98243-57-3 | 981-15-7 | 98026-79-0 | 979-92-0 | 97938-31-3 | 97938-30-2 | 97792-45-5 | 97-69-8 | Empty |
| Pseudoginsenoside RT1 | Chloramphenicol succinate sodium | Hupehenine | Ailanthone | 3-bromopyrrole-2,5-dione | SAH | Leachianone A | Sophoraflavanone G | Lappaconitine hydrobromide | Ac-Ala-OH | ||
| Empty | 97682-44-5 | 97-67-6 | 97-65-4 | 97-61-0 | 97-59-6 | 97-54-1 | 97540-22-2 | 97-53-0 | 97-41-6 | 973-67-1 | Empty |
| Irinotecan | (S)-Malic acid | Itaconic acid | 2-METHYLVALERIC ACID | Allantoin | Isoeugenol | S-Adenosyl-L-methionine disulfate tosylate | Eugenol | Ethyl chrysanthemate | 5,6,7-TRIMETHOXYFLAVONE | ||
| Empty | 97230-47-2 | 97230-46-1 | 97207-47-1 | 970-74-1 | 970-73-0 | 97005-76-0 | 96990-18-0 | 96-82-2 | 96702-03-3 | 96574-01-5 | Empty |
| Picfeltarraenin IA | Picfeltarraenin IB | Meisoindigo | (-)-Epigallocatechin | (+)-Gallocatechin | 4'-Methoxyflavanone | Momordin Ic | Lactobionic acid | Ectoine | Salvianolic acid A | ||
| Empty | 96553-02-5 | 96400-45-2 | 96382-91-1 | 96-26-4 | 961-29-5 | 961-07-9 | 96087-21-7 | 95975-55-6 | 959-33-1 | 959-23-9 | Empty |
| Gypsogenin-3-O-glucuronide | Luteolin 7-diglucuronide | Neonuezhenide | 1,3-Dihydroxyacetone | Isoliquiritigenin | 2'-Deoxyguanosine | Stylopine hydrochloride | Guggulsterone | 4-METHOXYCHALCONE | 4'-Methoxychalcone | ||
| Empty | 958-09-8 | 957-68-6 | 957-66-4 | 95-71-6 | 95480-80-1 | 95258-14-3 | 952068-57-4 | 951-78-0 | 951-77-9 | 95041-90-0 | Empty |
| 2'-Deoxyadenosine | 7-Aminocephalosporanic acid | Isolinderalactone | Pyrolin | 5-Hydroxy-7-acetoxy-8-methoxyflavone | Yadanziolide A | Parishin E | 2'-Deoxyuridine | 2'-Deoxycytidine | Erianin |
Keywords
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