Name: Chemerin/RARRES2 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01292
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 492

6-8日内发货

10 μg

¥ 820

6-8日内发货

20 μg

¥ 1,290

5日内发货

50 μg

¥ 2,480

5日内发货

100 μg

¥ 3,980

5日内发货

200 μg

¥ 6,420

5日内发货

500 μg

¥ 12,100

5日内发货

1 mg

¥ 17,300

5日内发货

生物活性

产品描述	Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon. It is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1. RARRES2 is secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. It is thought to act as a cell surface receptor, found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. RARRES2 is inhibited in psoriatic lesions,it is activated by tazarotene in skin rafts and in the epidermis of psoriatic lesions.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon. It is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1. RARRES2 is secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. It is thought to act as a cell surface receptor, found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. RARRES2 is inhibited in psoriatic lesions,it is activated by tazarotene in skin rafts and in the epidermis of psoriatic lesions.
种属	Human
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	Q99969
氨基酸序列	Glu21-Ser157
蛋白构建	Glu21-Ser157
蛋白纯度	Greater than 95% as determined by SEC-HPLC.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	TIG2, Tazarotene-induced gene 2 protein, Retinoic acid receptor responder protein 2, RAR-responsive protein TIG2, RARRES2, Chemerin
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.

化学信息

分子量	16-20 KDa (reducing condition)
颜色	White
物理性状	Solid

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Chemerin/RARRES2 Protein, Human, Recombinant (His)

Chemerin/RARRES2 Protein, Human, Recombinant (His)

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