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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ADAMTSL2 Polyclonal Antibody

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货号 TMAB-02306

Anti-ADAMTSL2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ADAMTSL2。Anti-ADAMTSL2 Polyclonal Antibody 可用于 WB。

Anti-ADAMTSL2 Polyclonal Antibody

Anti-ADAMTSL2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02306

Anti-ADAMTSL2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ADAMTSL2。Anti-ADAMTSL2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADAMTSL2 Polyclonal Antibody is a Rabbit antibody targeting ADAMTSL2. Anti-ADAMTSL2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ADAMTS (A Disintegrin And Metalloproteinase Domain with Thrombospondin type 1 Modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an amino-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a carboxy-terminus that contains a varying number of Thrombospondin type 1 (TSP-1) motifs. ADAMTS-L2 (ADAMTS-like protein 2) is a 951 amino acid secreted protein that is highly expressed in lung, kidney and liver. Mutations in the gene encoding ADAMTS are the cause of geleophysic dysplasia, an autosomal recessive disorder characterized by cardiac vavular anomalies, short stature, thick skin and brachydactyly. In individuals affected with geleophysic dysplasia, there is a significant increase in total active TGF-beta 1 and nuclear locations of p-SAMD2 in fibroblasts. Interestingly, ADAMTS-L2 interacts with LTBP-1, a glycoprotein that is part of the platelet-derived TGF-beta 1 complex.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADAMTSL2
抗原种属
Human
基因名称
ADAMTSL2
基因ID
9719
蛋白名称
ADAMTS-like protein 2
Uniprot ID
Q86TH1
功能
Defects in ADAMTSL2 are the cause of geleophysic dysplasia [MIM:231050]. Geleophysic dysplasia is an autosomal recessive disorder characterized by short stature, brachydactyly, thick skin and cardiac valvular anomalies often responsible for an early death.
化学信息
分子量Theoretical: 102 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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