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Anti-NOV/CCN3 Antibody (5D628)

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Anti-NOV/CCN3 Antibody (5D628)
产品编号 TMAY-00538
别名 nephroblastoma overexpressed

Anti-NOV/CCN3 Antibody (5D628) 是一种 Rabbit 抗体,靶向 NOV/CCN3。Anti-NOV/CCN3 Antibody (5D628) 可用于 ELISA。

Anti-NOV/CCN3 Antibody (5D628)
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Anti-NOV/CCN3 Antibody (5D628)

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Anti-NOV/CCN3 Antibody (5D628)
产品编号 TMAY-00538 别名 nephroblastoma overexpressed

Anti-NOV/CCN3 Antibody (5D628) 是一种 Rabbit 抗体,靶向 NOV/CCN3。Anti-NOV/CCN3 Antibody (5D628) 可用于 ELISA。

规格价格库存数量
20 μL
¥ 795
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100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-NOV/CCN3 Antibody (5D628) is a Rabbit antibody targeting NOV/CCN3. Anti-NOV/CCN3 Antibody (5D628) can be used in ELISA.
别名nephroblastoma overexpressed
Ig Type
Rabbit IgG
克隆号
5D628
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CCN3 / NOV / IGFBP9 (rh CCN3 / NOV / IGFBP9; TMPY-01307; NP_002505.1; Met 1-Met 357).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Protein NOV homolog, also known as Nephroblastoma-overexpressed gene protein homolog, NOV, and CCN3, is a putative ligand for integrin receptors, is tightly associated with the extracellular matrix, and mediates diverse cellular functions, including cell adhesion and proliferation. CCN3 has been shown to negatively regulate growth although it promotes migration in a cell type-specific manner. This secreted protein belongs to the CCN family, and its expression was observed in a broad variety of tissues from the early stage of development, and altered expression of CCN3 has been observed in a variety of tumors, including hepatocellular carcinomas, Wilm's tumors, Ewing's sarcomas, gliomas, rhabdomyosarcomas, and adrenocortical carcinomas. Mature CCN3 protein has five distinct modules and truncated protein variants with altered function are found in many cancers. CCN3 acts through the core stem cell signaling pathways including Notch and Bone Morphogenic Protein, connecting CCN3 with the modulation of self-renewal and maturation of some cell lineages including hematopoietic, osteogenic, and chondrogenic. CCN3 may affect the extracellular environment of the niche for hematopoietic stem cells. CCN3 has emerged as a key player in stem cell regulation, hematopoiesis, and a crucial component within the bone marrow microenvironment.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CCN3 / NOV / IGFBP9 Protein (TMPY-01307)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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